Prediction of protein–protein interactions based on elastic net and deep forest

Pathway-Based Genomics Prediction using Generalized Elastic Net

We present a novel regularization scheme called The Generalized Elastic Net (GELnet) that incorporates gene pathway information into feature selection. The proposed formulation is applicable to a wide variety of problems in which the interpretation of predictive features using known molecular interactions is desired. The method naturally steers solutions toward sets of mechanistically interlink...

Elastic Net-based Parcellation (ENPA)

Short term electric load prediction based on deep neural network and wavelet transform and input selection

Electricity demand forecasting is one of the most important factors in the planning, design, and operation of competitive electrical systems. However, most of the load forecasting methods are not accurate. Therefore, in order to increase the accuracy of the short-term electrical load forecast, this paper proposes a hybrid method for predicting electric load based on a deep neural network with a...

The elastic net algorithm and protein structure prediction

Predicting protein structures from their amino acid sequences is a problem of global optimization. Global optima (native structures) are often sought using stochastic sampling methods such as Monte Carlo or molecular dynamics, but these methods are slow. In contrast, there are fast deterministic methods that find near-optimal solutions of well-known global optimization problems such as the trav...

Adaptive Elastic Net: An Improvement of Elastic Net

Lasso proved to be an extremely successful technique for simultaneous estimation and variable selection. However lasso has two major drawbacks. First, it does not capture any grouping effect and secondly in some situations lasso solutions are inconsistent. To overcome inconsistency recently adaptive lasso was proposed where adaptive weights are used for penalizing different coefficients. Adapti...